Galanthamine is natural extracted from Lycoris radiate, is a tertiary alkaloid derived from snowdrop and closely related species. Galanthamine extract is specific, competitive and reversible acetylcholinesterase inhibitor. It acts as a reversible competitive acetylcholinesterase (AChE) inhibitor, while acts weaker on butyrylcholinesterase (BuChE). It is used in the treatment of disorders of the central nervous system and may be used as an antidote to nonpolarizing muscle relaxants. It is also an allosteric modulator at nicotinic cholinergic receptor sites potentiating cholinergic nicotinic neurotransmission. Both the acetylcholine and nicotine receptors have been suggested as areas related to cognitive impairment. Initially, Galanthamine extract was used in anesthesiology to antagonize the effects of non-depolarizing muscle relaxants, and since then it was rapidly introduced in other areas of medicine, i.e. neurology, ophthalmology, gastroenterology, intensive care and resuscitation, cardiology, physiotherapy.
Galanthamine extract is a product with broad therapeutic index, allowing "soft" manifestation of its effect with individual dosing depending on the particular case.
Galantamine has been used for decades in Eastern Europe and the USSR for various indications such as treatment of myasthenia, myopathy, and sensory and motor dysfunction associated with disorders of the central nervous system.
1. It also can be applied to puerilism, posttraumatic apoplexy, polyneuritis and radiculitis.Clinic function: mainly used in myasthenia gravis, poliovirus quiescent stage and sequela.
2. It also in polyneuritis, funiculitis and sensorimotor barrier caused by nervous system disease or traumatism.
3. It’s major used in Alzheimer's disease, has the principal function for dement and dysmnesia caused by organic brain damage.
2. Health Food